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5-HYDROXYINDOLE-3-ACETIC ACID

CAS No. 54-16-0

5-HYDROXYINDOLE-3-ACETIC ACID( 5-HIAA )

Catalog No. M19623 CAS No. 54-16-0

5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors and levels of these substances may be measured in the urine to test for carcinoid tumors (NCI).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-HYDROXYINDOLE-3-ACETIC ACID
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors and levels of these substances may be measured in the urine to test for carcinoid tumors (NCI).
  • Description
    5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors and levels of these substances may be measured in the urine to test for carcinoid tumors (NCI).
  • In Vitro
    5-Hydroxyindole-3-acetic acid (5HIAA) is a metabolite issued from serotonin metabolism, and the latter is synthetized from the essential amino acid tryptophan. Serotonin is mainly metabolised by monoamine oxidase in the liver and the lungs.
  • In Vivo
    ——
  • Synonyms
    5-HIAA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    54-16-0
  • Formula Weight
    191.18
  • Molecular Formula
    C10H9NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM;Ethanol: 50 mg/mL
  • SMILES
    OC(=O)Cc1c[nH]c2ccc(O)cc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Corcuff JB et al. Urinary sampling for 5HIAA and metanephrines determination: revisiting the recommendations. Endocr Connect. 2017 Aug;6(6):R87-R98.
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